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10 lip 2024 · Our results show that the cerebellum is a thirst-modulating brain area and that asprosin–Ptprd signaling may be a potential therapeutic target for the management of thirst disorders.
19 cze 2024 · Advances in large-scale single-unit human neurophysiology, single-cell RNA sequencing, spatial transcriptomics and long-term ex vivo tissue culture of surgically resected human brain tissue have...
17 lip 2024 · Perineuronal nets (PNNs) are densely packed extracellular matrices that cover the cell body of fast-spiking inhibitory neurons. PNNs stabilize synapses inhibiting synaptic plasticity. Here we...
We then highlight three paradigm shifts: (1) the switch from studying whole brain areas or single neurons to studying intermingled neural circuits at cellular resolution, (2) the increased focus on computation at the level of emergent properties in large neural populations, and (3) the transition from measuring neural activity in highly controll...
2 lut 2023 · Nature Neuroscience - The authors map thalamic synapses onto layer 2/3 mouse visual cortex neurons, showing they are sparse, small and heterogeneously distributed. Modeling these data suggests...
Lecture 3. Master Class: Human Brain Dissection (in-class dissection—video not recorded; lecture notes not provided) Lecture 4: Cognitive Neuroscience Methods I (PDF - 4.2MB)
Predictive puzzles. This week, Abigail Greene at Yale University School of Medicine in New Haven, Connecticut, and her colleagues tackle the reliability of predictive modelling in cognitive...