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  1. 7 sie 2023 · OIC may present immediately when a patient takes the opioid, or it may present gradually during opioid therapy. In association with constipation, patients may also develop other GI side effects like nausea, vomiting, bloat, abdominal pain, and straining.

  2. The objective of this study was to provide an overview of opioid-induced constipation (OIC) and its influence on disease burden and quality of life (QOL). Methods: This is a narrative review. Results: For many patients, opioid-related side effects, the most common being OIC, have the potential to significantly impair patients’ QOL.

  3. 13 mar 2024 · Constipation can be more than just uncomfortable. If you don’t treat it, you might have pain and cramping in your gut, and your belly may stick out. Eventually your intestines might get blocked,...

  4. 5 maj 2014 · Although opioids offer potent analgesia for severe acute and chronic noncancer pain, adverse gastrointestinal effects potentially undermine their clinical utility. In particular, between 40% and 95% of patients develop opioid-induced constipation (OIC).

  5. 15 gru 2016 · Opioid-induced constipation (OIC) is the most frequently reported and persistent side effect in patients receiving opioids for analgesia . This review aims to evaluate the current understanding of OIBD and provide timely evidence-based recommendations for the management of patients affected by this condition.

  6. Despite their analgesic efficacy, opioids are associated with side-effects including lethargy, pruritus, nausea, gastro-oesophageal reflux, and constipation. 1,2 Such side-effects can limit the ability of the health-care provider to escalate the dose of opioids and can even result in their discontinuation. 3,4 Unlike opioid side-effects that ...

  7. Opioids are potent analgesics used for the treatment of acute and chronic pain. Side-efects are common and among the most bothersome are those associated with opioid-induced bowel dysfunction, which includes opioid-induced constipation.