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Myo-inositol is a novel treatment for women with PCOS that claimed to have improved fertility rate in this population. This systematic review and meta-analysis examined the effect of myo-inositol on pregnancy rate, menstrual cycle, and adverse effects from randomized controlled trials (RCTs).
Additionally, a recent review of RCTs showed that the daily use of 4 g myo-inositol was effective in reducing the gonadotropin dose and stimulation window in women undergoing IVF. These data subtend a specific action as a gonadotropin-sensitizer agent at the ovary level.
2 sty 2024 · To inform the 2023 international evidence-based guidelines in PCOS, this systematic review and meta-analysis evaluated the efficacy of inositol, alone or in combination with other therapies, in the management of PCOS. Medline, PsycInfo, EMBASE, All EBM, and CINAHL from inception until August 2022.
12 wrz 2024 · Given the potential of Myo-inositol therapy to improve sperm quality and male fertility, but with conflicting results reported in previous studies, we conducted a systematic review and meta-analysis to investigate the effects of Myo-inositol on sperm factors and pregnancy rate.
Myoinositol supplement increase clinical pregnancy rate in infertile women undergoing ovulation induction for ICSI or IVF-ET. It may improve the quality of embryos, and reduce the unsuitable oocytes and required amount of stimulation drugs.
1 cze 2023 · This randomized controlled trial demonstrated that a combined myo-inositol, probiotic, and micronutrient supplement in women planning conception did not change the overall time-to-natural-conception or clinical pregnancy rates up to one year, nor the live birth rates.
– Myo-inositol (MYO) usually rep-resents a therapeutic option for female infertility associated with insulin resistance. Recently, sev-eral evidences are accumulating about the poten-tial use of MYO for the treatment of male infertility. This article summarizes the rationale for MYO in the treatment of male infertility.