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Learn about the function, structure and classification of muscarinic receptors, a type of acetylcholine receptor that forms G protein-coupled complexes. Find out how they are involved in the autonomic nervous system, the neuromuscular junction and the central nervous system.
8 sie 2023 · Muscarinic receptors are G-coupled protein receptors involved in the parasympathetic nervous system. The only exception to these receptors is the sweat glands, which possess muscarinic receptors but are part of the sympathetic nervous system.
6 cze 2014 · The muscarinic acetylcholine receptors are a subfamily of G protein-coupled receptors that regulate numerous fundamental functions of the central and peripheral nervous system. The past few...
Learn about muscarinic acetylcholine receptors, a type of G protein-coupled receptor that is a target for drugs in various diseases. Find chapters and articles on their structure, function, subtypes, allosteric modulation, and role in neuroinflammation and Alzheimer's disease.
Radioligand-binding studies have been used to characterize muscarinic receptors; The binding properties of the antagonist pirenzepine led to the initial classification of muscarinic receptors; Transgenic mice are being generated to assess the functions of receptor subtypes in vivo
This review will focus on central muscarinic receptors, discussing the data implicating them in the pathophysiology of psychiatric disorders, such as schizophrenia, bipolar disorder, major depressive disorder (MDD), and substance abuse, as well as neurological diseases such as Alzheimer's and Parkinson's disease.
1 sty 2022 · Learn about the structure, distribution, and function of muscarinic acetylcholine receptors (mAChRs), a class of G protein-coupled receptors activated by ACh. Find out how mAChRs mediate diverse actions in the CNS and periphery, and how they are modulated by ligands and mutations.
