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  1. If you qualify, your treatment team can recommend one of our clinical trials if they feel it may help improve your condition. You will find two important resources here, including: MSKs Hereditary Colorectal Cancer Family Registry. MSK’s clinical trials for colorectal cancer.

    • Clinical Trials

      At MSK, we’re running one of the largest clinical trials...

  2. At MSK, we’re running one of the largest clinical trials programs for cancer in the country. Patients who choose to participate in a trial at MSK receive the most advanced cancer treatment available, sometimes years before it’s offered anywhere else.

  3. 2 gru 2020 · This randomized phase 3 trial showed that front-line pembrolizumab was superior to chemotherapy with respect to progression-free survival in patients with MSI-H–dMMR metastatic colorectal...

  4. 5 cze 2022 · In this study involving patients with mismatch repair–deficient, locally advanced rectal cancer, treatment with neoadjuvant PD-1 blockade alone resulted in a clinical complete response — as ...

  5. 4 cze 2023 · Methods. We conducted a multicenter, unblinded, noninferiority, randomized trial of neoadjuvant FOLFOX (with chemoradiotherapy given only if the primary tumor decreased in size by <20% or if...

  6. 10 sie 2022 · Organ preservation is achievable in half of the patients with rectal cancer treated with total neoadjuvant therapy, without an apparent detriment in survival, compared with historical controls treated with chemoradiotherapy, TME, and postoperative chemotherapy.

  7. 9 sty 2024 · In this secondary analysis of a randomized clinical trial, we found that clinical tumor response grade at restaging was associated with OP and survival in patients with locally advanced rectal cancer treated with neoadjuvant therapy.

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