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1 cze 2023 · The results showed that DRG cells from NOD (and NOD.RAG-2-/-) mice have a different gene expression pattern compared to C57BL/6 mice, indicating that DRG cells from NOD mice have a functional impairment. Microarray analyses indicate that these functional changes mainly affect pathways of inflammatory processes and immune response, as well as ...
H&E-stained sections of dorsal root ganglia (DRG) were evaluated blindly for histopathological lesions by a board-certified pathologist (A.D.M.); scoring was based on the presence and...
21 cze 2024 · We observed >500 cell-type–specific genes in the DRG or TG that are expressed significantly more in human than in mice (log 2 FC > 0.5 and adjusted P value < 0.05 human versus all nonhuman species; table S11). For example, several neuropeptides, GPCRs, and ion channels that are restricted to specific cell types in mice are expressed more ...
23 sty 2023 · Single-nuclei RNA-seq analysis of mouse DRG. We integrated expression data from 37,384 nuclei from five mouse DRGs (Table 1, Supplementary Data 1).
27 gru 2013 · A Practical Guide to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year.
23 lut 2024 · The histopathological examination of tissue is the cornerstone of cancer diagnosis globally. It is based on the staining of tissue samples with histochemical dyes, such as haematoxylin and eosin (H&E), to highlight cellular components for visual interpretation by pathologists.
4 mar 2024 · We used this resource to reveal a remarkable degree of morphological and physiological diversity across the transcriptionally distinct DRG neuron subtypes. This mouse DRG neuron toolkit should enable analyses of the neuronal building blocks of somatosensation.
