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23 sty 2023 · We generated a transcriptome atlas of mouse, guinea pig, cynomolgus monkey, and human DRGs by implementing a common laboratory workflow and multiple data-integration approaches to generate...
23 lut 2024 · The histopathological examination of tissue is the cornerstone of cancer diagnosis globally. It is based on the staining of tissue samples with histochemical dyes, such as haematoxylin and eosin (H&E), to highlight cellular components for visual interpretation by pathologists.
The dorsal root ganglion (DRG) houses the cell bodies of primary sensory neurons and projects axons to both the peripheral site of injury and the dorsal horn of the spinal cord. Hence, it is conceivable that the DRG is a major site of nociceptive processing in both adaptive and maladaptive pain states.
11 lut 2016 · Here, we describe a simple, step-by-step protocol for the swift isolation of mouse DRG, which can be enzymatically dissociated to produce fully differentiated primary neuronal cultures, or processed for downstream analyses, such as immunohistochemistry or RNA profiling.
4 mar 2024 · We used this resource to reveal a remarkable degree of morphological and physiological diversity across the transcriptionally distinct DRG neuron subtypes. This mouse DRG neuron toolkit should enable analyses of the neuronal building blocks of somatosensation.
Dorsal Root Ganglion (Azan) A cross-section of a dorsal root ganglion stained with azan to make it easier to see nerve fibers and connective tissue. Compare this slide with MH 050 Dorsal Root Ganglion (H&E). with large nuclei and prominent, red nucleoli.
H&E-stained sections of dorsal root ganglia (DRG) were evaluated blindly for histopathological lesions by a board-certified pathologist (A.D.M.); scoring was based on the presence and...
