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23 sty 2023 · We generated a transcriptome atlas of mouse, guinea pig, cynomolgus monkey, and human DRGs by implementing a common laboratory workflow and multiple data-integration approaches to generate...
23 lut 2024 · The histopathological examination of tissue is the cornerstone of cancer diagnosis globally. It is based on the staining of tissue samples with histochemical dyes, such as haematoxylin and eosin (H&E), to highlight cellular components for visual interpretation by pathologists.
11 lut 2016 · Here, we describe a simple, step-by-step protocol for the swift isolation of mouse DRG, which can be enzymatically dissociated to produce fully differentiated primary neuronal cultures, or processed for downstream analyses, such as immunohistochemistry or RNA profiling.
21 cze 2024 · Abstract. Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are specialized to detect and transduce diverse environmental stimuli to the central nervous system.
12 maj 2023 · Deep learning-based virtual staining of unstained histological tissue is presented. •. We show that increasing the network capacity produces better virtual staining. •. Our method uses regular brightfield microscopy and is widely applicable. •. Virtual staining has great potential in reducing the need for chemical staining. The bigger picture.
PIEZO1 and PIEZO2 expression in mouse DRG.(A,B) Adjacent DRG slices viewed at low magnification (10× objective) showing faint brown punctuate staining by the PIEZO1 RNA probe (A) and dark brown staining with the PIEZO2 probe (B).(C,D) Specific DRG regions examined at higher magnification (40× objective). The red circles circumscribe several (∼10) small DRG neurons with punctuate PIEZO1 ...
H&E-stained sections of dorsal root ganglia (DRG) were evaluated blindly for histopathological lesions by a board-certified pathologist (A.D.M.); scoring was based on the presence and...
