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1 cze 2023 · Methods: Histopathological analysis by electron and optical microscopy in DRG samples, and mRNA expression analyzes by the microarray technique in DRG and blood leukocyte samples from NOD and C57BL/6 mice were performed.
H&E-stained sections of dorsal root ganglia (DRG) were evaluated blindly for histopathological lesions by a board-certified pathologist (A.D.M.); scoring was based on the presence and severity of...
23 sty 2023 · Our integrative and comparative analysis of DRGs from mice, guinea pigs, cynomolgus monkeys, and humans identified diverse subtypes of DRG sensory neurons in each species and showed that these...
21 cze 2024 · As implicated by the overlap in enriched cell-type–specific gene ontology terms between species (fig. S8E), the evolutionarily conserved expression patterns of these genes suggest that functional studies of these genes in mice DRG/TG could be predictive in many cases to their function in humans.
11 lut 2016 · Here, we describe a simple, step-by-step protocol for the swift isolation of mouse DRG, which can be enzymatically dissociated to produce fully differentiated primary neuronal cultures, or processed for downstream analyses, such as immunohistochemistry or RNA profiling.
Download scientific diagram | Comparative histology of DRG injected with either vehicle or RTX. Hematoxylin and eosin (H&E) preparation of DRG parenchyma from lumbar DRG at ×40...
Download scientific diagram | DRG neuronal pathology: (A) Representative H&E-stained histology sections of lumber DRG from (A) vehicle-treated and (B) 109-treated YG8R mice.
