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The dramatic decline in smallpox fatalities in response to Jenner's vaccine can be traced in the chart, which shows the number of deaths due to smallpox as a share of all deaths in London from 1629 to 1902.
28 lis 2022 · The strength and longevity of smallpox vaccination campaigns globally, combined with current demographic heterogeneity, have shaped the epidemiological landscape today, revealing substantial geographical variation in orthopoxvirus susceptibility.
30 mar 2023 · The studies suggested that smallpox is 80.7% efficacious to prevent human monkeypox and the immunity provided by prior smallpox vaccination is long-lasting. Moreover, the smallpox vaccination decreases the risk of human monkeypox by 5.2-folds.
The estimated annual number of deaths caused by several vaccine-preventable diseases, based on statistical modeling. Estimates come with wide uncertainties, especially for countries with poor vital registration.
Patients are most contagious after the rash appears. 1 The mortality rate for the most pathogenic variety of smallpox, variola major, was about 30%.
21 gru 2020 · This study presents the complete historical weekly record of smallpox mortality in London over more than 250 years (1664-1930), describes it using spectral analyses, and discusses it in the context of events and interventions that might have influenced infectious disease dynamics.
14 lis 2007 · To provide a context for viewing vaccine-preventable disease morbidity and mortality, we describe elements of the US national immunization program, including development of immunization policy, vaccine distribution and coverage assessment, vaccine safety monitoring, and surveillance.