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Zygosity refers to the genetic makeup of the pregnancy, or the number of zygotes that become fertilized leading to a multiple birth. Twins, in rarer cases triplets, quadruplets (four), quintuplets (five), arising from a single fertilized ovum are termed monozygotic (MZ).
7 sty 2021 · Our analysis demonstrates that in 15% of monozygotic twins a substantial number of mutations are specific to one twin but not the other.
1 sty 2020 · A closer look at the frequencies of the East Flanders Prospective Twin Survey (Derom and Derom, 2005), where genetic assessment of zygosity is nearly 100%, reveals that 44% of spontaneous twins are monozygotic, compared to 16% of spontaneous triplets. However, when one counts the number of zygotes that underwent splitting, one should also count ...
10 lip 2024 · Monozygotic (MZ) twins are believed to arise from the fission of a single fertilized embryo at different stages. Monochorionic MZ twins, who share one chorion, originate from the splitting of the inner cell mass (ICM) within a single blastocyst.
birth. Twins, in rarer cases triplets, quadru-plets (four), quintuplets (ve), arising from a single fertilized ovum are termed mono-zygotic (MZ). The rst identical quintuplets known to have survived their infancy were the Canadian Dionne quintuplets, all ve of which survived to adulthood (. Fig. 3.1).
13 sty 2021 · Looking at 381 monozygotic twin pairs and 2 triplets, the authors first estimated the number of postzygotic mutations present in one twin but not the other.
Results. Genomic differences between monozygotic twins. We first esti-mated the number of discordant postzygotic mutations in pairs of monozygotic twins (381 twin pairs; 2 triplets) by comparing sequence variation in somatic tissues (1 adipose, 204 buccal and .
