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21 cze 2015 · From the considered model, the probability of monozygotic twins is found to be (1/2) K, and we discover that the probability of monozygotic quadruplets, or triplets as in the case of the death of an embryo, is (1/8) K, where K is a species-specific integer
7 sty 2021 · When DNA isolated from the blood of monozygotic twins is sequenced and compared, some of the differences seen may be due to somatic mutations in blood cells or their precursors. Such mutations...
1 sty 2020 · If two genetically distinct populations of cells were formed before repulsion, another distinct cellular differentiation event would have to occur in at least one of the resultant cell populations at the same embryological state in order to produce monozygotic triplets.
10 lip 2024 · Monozygotic (MZ) twins are believed to arise from the fission of a single fertilized embryo at different stages. Monochorionic MZ twins, who share one chorion, originate from the splitting of the inner cell mass (ICM) within a single blastocyst.
13 sty 2021 · Looking at 381 monozygotic twin pairs and 2 triplets, the authors first estimated the number of postzygotic mutations present in one twin but not the other.
10 gru 2011 · Monozygotic (MZ) twins originate when a single egg is fertilized to form one zygote, which then divides into two embryos. Although they share the same genotype they are not phenotypically identical. Within monozygotic twin pairs there can be significant discordance for some multi-factorial diseases [ 1 , 2 ] and they also show a wide range of ...
Zygosity refers to the genetic makeup of the pregnancy, or the number of zygotes that become fertilized leading to a multiple birth. Twins, in rarer cases triplets, quadruplets (four), quintuplets (five), arising from a single fertilized ovum are termed monozygotic (MZ).