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7 sty 2021 · Furthermore, their mutation sharing suggests that two of the triplets were formed from the descendants of the same cell whereas the third was formed from a different set of cells.
13 sty 2021 · Looking at 381 monozygotic twin pairs and 2 triplets, the authors first estimated the number of postzygotic mutations present in one twin but not the other.
10 lip 2024 · In mouse embryos, recent findings suggest that cell fate has diverged between the cells as early as the two-cell stage, with one blastomere exhibiting stronger totipotency than the other (Papaioannou et al. 1989; Casser et al. 2017; Hupalowska et al. 2018; Wang et al. 2018; Jin et al. 2022).
10 gru 2011 · Monozygotic (MZ) twins originate when a single egg is fertilized to form one zygote, which then divides into two embryos. Although they share the same genotype they are not phenotypically identical.
27 lut 2009 · The difference between monozygotic and dizygotic twinning is, exactly as it should be by definition, all and only about the difference between the presence of only one, or of two, diploid nuclei in the zygote, and thus embryonic cells of one genotype or two.
1 lip 2014 · Different number of triplets or differential activation of copy genes have been implicated in the variable expression of diseases such as Steinert's myotonic dystrophy in MZ twins. Still there are few data concerning repeat expansion disorders in twins.
1 wrz 2001 · In this review, we describe a number of intrauterine effects and genetic mechanisms that may result in phenotypic, genotypic, and epigenetic differences between monozygous twins. Newer molecular techniques are resulting in such differences being increasingly commonly recognised.
