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10 lip 2024 · Cases of MZ twins from IVF clinics were found by using combinations of terms including ‘monozygotic twins’ with ‘IVF case report’, ‘ART’, ‘single embryo transfer’, or ‘dichorionic’. The papers retrieved were categorized based on the implicated mechanisms or as those with unexplained mechanisms.
Zygosity refers to the genetic makeup of the pregnancy, or the number of zygotes that become fertilized leading to a multiple birth. Twins, in rarer cases triplets, quadruplets (four), quintuplets (five), arising from a single fertilized ovum are termed monozygotic (MZ).
7 sty 2021 · When DNA isolated from the blood of monozygotic twins is sequenced and compared, some of the differences seen may be due to somatic mutations in blood cells or their precursors. Such...
1 wrz 2001 · In this review, we describe a number of intrauterine effects and genetic mechanisms that may result in phenotypic, genotypic, and epigenetic differences between monozygous twins. Newer molecular techniques are resulting in such differences being increasingly commonly recognised.
1 sty 2020 · The splitting-generation dependent differences expected from the various combinations might explain why one pair of monozygotic twins is more alike than another pair, or similarity/dissimilarity between monozygotic triplets.
1 lip 2014 · Different number of triplets or differential activation of copy genes have been implicated in the variable expression of diseases such as Steinert's myotonic dystrophy in MZ twins. Still there are few data concerning repeat expansion disorders in twins.
The cause and mechanism of zygotic splitting are unknown. However, four axioms exist that relate to monozygotic twinning. First, monozygotic twins occur in a remarkably constant frequency among dif-ferent racial groups.
