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7 sty 2021 · We first estimated the number of discordant postzygotic mutations in pairs of monozygotic twins (381 twin pairs; 2 triplets) by comparing sequence variation in somatic tissues (1 adipose, 204...
13 sty 2021 · The study of monozygotic twins has long been used to dissect the contributions of environmental influences versus genetic variation, the assumption being that the genetic background of siblings...
1 paź 2021 · Scientists have discovered DNA methylation differences that are unique to identical twins, helping to unravel the exact molecular events that lead to division of a zygote. Monozygotic twins, or identical twins, result from the fertilisation of a single egg with a single sperm.
4 cze 2019 · To uncover epigenetic and transcriptomic factors that may modify an ALS phenotype, we used a cohort of Australian monozygotic twins (n = 3 pairs) and triplets (n = 1 set) that are discordant...
The goal of this study is to explore the differential expression of miRNAs within MZ twin pairs, and aimed to find new biomarkers for distinguishing MZ twins. Thus, the miRNA expression profiles of seven pairs of healthy MZ twins of different sex and age were analyzed by miRNA microarray.
1 sty 2019 · Cite. https://doi.org/10.1016/j.fsigen.2018.09.011 Get rights and content. Highlights. •. The miRNA expression profiles of four healthy monozygotic twin pairs were investigated. •. An average of 158 miRNAs was detected in each individual. •. 14% miRNAs showed differences in expression within each pair of monozygotic twins on average. •.
1 lip 2019 · In this study, we explore the potential of using epigenetic markers, specifically circular RNAs (circRNAs), a type of non-coding RNA (ncRNA), to identify MZTs, and investigate the unique expression patterns of circRNAs within pairs of MZTs, enabling effective differentiation.
