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19 sie 2020 · Here, we review the virology of mumps, licensed mumps vaccines, and the typical immune responses elicited following mumps vaccination. Furthermore, we discuss the limitations and challenges of the currently licensed mumps vaccines and provide strategies for the development of an improved mumps vaccine.
19 gru 2013 · A monovalent mumps vaccine lot is used to characterize the performance of the mumps potency assay with international reference standards. Degradation products are neither identified nor quantified . Currently, the minimum potency of the mumps vaccine used varies between brands used [summarized by Su et al. ] .
31 sty 2005 · These vaccines are produced by growing the virus in cell cultures or in embryonated chicken eggs. The virus is then purified, formulated with a stabilizer such as gelatine or sorbitol and lyophilized. Mumps vaccines are available as a monovalent vaccine, a bivalent measles-mumps vaccine, or as a trivalent measles-mumps-rubella vaccine (MMR).
10 mar 2014 · To understand the biological characterization of the isolated SP-A virus exhibited by immunization with the new mumps vaccine, we performed viral nucleic acid detection in throat swabs collected at days 0, 4, 7, 10, 14, and 28 post-vaccination from all of the vaccine-immunized individuals.
1 wrz 2020 · Our meta-analysis provides estimates of primary and secondary vaccine failure, which are essential to improve the accuracy of mathematical and statistical modelling to understand and predict the occurrence of future measles, mumps, and rubella outbreaks in countries with high vaccine uptake.
2 wrz 2022 · We conducted cost-effectiveness analyses on routine monovalent mumps vaccine immunization programs for a 1-year old cohort in Japan. In this study, the single-dose program was at 1 year old, while the two-dose program with second dose uptakes was at 5 years old.
This review considers the disease burden due to mumps; summarizes studies on the immunogenicity, efficacy, and safety of different strains of mumps vaccine; and highlights lessons learned about implementing mumps immunization in different countries.
