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28 kwi 2022 · In a recent presentation to the scientific directors, Yang demonstrated how 3-D structures of protein-DNA complexes provide unique insights into dynamic interactions between proteins and their substrates in health and disease.
24 lut 2023 · Here, we present a compilation of DNA and protein databases, as well as bioinformatic tools for phylogenetic reconstruction and a wide range of studies on molecular evolution.
14 lis 2024 · Evo generalizes across DNA, RNA, and proteins, enabling zero-shot function prediction competitive with domain-specific language models and the generation of functional CRISPR-Cas and transposon systems, representing the first examples of protein-RNA and protein-DNA codesign with a language model.
24 lip 2024 · Model DNA to fascynujący projekt edukacyjny, doskonały sposób na zgłębianie tajników genetyki i funkcjonowania organizmów. Podpowiemy, jak skutecznie stworzyć model DNA. Wizualizacja struktury DNA ułatwia zrozumienie jego kluczowej roli w biologii.
9 lut 2024 · Our findings reveal that DNA shape readout mechanisms of a core target are quantitatively affected by flanking regions, including extended flanking regions, providing valuable insights into the...
A key question in the YY1 field is how a DNA-binding TF can act as both a transcriptional activator and repressor. Multiple mechanisms have been suggested, including post-translational modifications of YY1 (Yao et al., 2001) and co-factor dependency (Gordon et al., 2006).
28 lis 2005 · YY1 is a ubiquitous and multifunctional zinc-finger transcription factor (also known as δ, NF-E1, UCRBP, and CF1) member of the Polycomb Group protein family, a group of homeobox gene receptors...
