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How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as...
- Tandem Repeats and Morphological Variation
Of course, the Runx-2 protein has both a polyglutamine...
- Eukaryotic Genome Complexity
How many genes are there? This is frequently the first...
- Recombinant DNA Technology and Transgenic Animals
Although recombinant DNA technology first emerged in the...
- Genetic Code
Right away, researchers knew that the genetic code was more...
- Errors in DNA Replication
After James Watson and Francis Crick published their model...
- Molecular Events of DNA Replication
As previously mentioned, the location at which a DNA strand...
- Isolating Hereditary Material
How did scientists determine that DNA is the hereditary...
- Not Junk Dna
Much of the human genome is made up of transposable...
- Tandem Repeats and Morphological Variation
23 lut 2024 · Protein translation, also known as protein synthesis, is a fundamental biological process that involves the conversion of the nucleotide sequence in mRNA into a specific sequence of amino...
The genetic information in DNA is transcribed to mRNA and then translated to proteins, which form the building blocks of life. Translation, or protein synthesis, is hence a central cellular process. We have developed a gene-sequence-specific ...
Transcription and RNA processing are followed by translation, the synthesis of proteins as directed by mRNA templates. Proteins are the active players in most cell processes, implementing the myriad tasks that are directed by the information encoded in genomic DNA.
27 lut 2014 · We present our analysis in the following sequence: 1) the definition of codon-based models and an analysis of the simulation algorithms; 2) the effect of the update rules in codon-based models; 3) a new PBN model for mRNA translation; 4) a comparison of the different modelling methodologies with added biological complexities; and 5) discussion.
29 lip 2010 · We exemplified and discussed other possible ways of model utilisation, as it may help in examining protein-protein interactions, metabolic pathways, gene annotation, ribosome queueing, protein folding, and translation initiation.
14 sie 2015 · Here, we propose to fit models of translation onto ribosome profiling measurements, which record snapshots of the locations of actively translating ribosomes on mRNAs from millions of cells.
