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  1. Mirena ® (levonorgestrel-releasing intrauterine system) 52 mg is indicated for prevention of pregnancy for up to 8 years; replace after the end of the eighth year. Mirena is indicated for the treatment of heavy menstrual bleeding for up to 5 years in women who choose to use intrauterine contraception as their method of contraception; replace ...

  2. 18 lip 2024 · Dosage form: intrauterine device. Drug classes: Contraceptives, Progestins. Medically reviewed by Drugs.com. Last updated on Jul 18, 2024. Dosing Over Time. Mirena contains 52 mg of levonorgestrel (LNG) released in vivo, at a rate of approximately 21 mcg/day after 24 days.

  3. 29 kwi 2022 · The 52-mg levonorgestrel-releasing intrauterine system maintains an excellent safety profile and contraceptive efficacy through 8 years. For years 6 to 8, the 3-year Pearl Index (95% confidence interval) was 0.28 (0.03–1.00) with a 3-year cumulative failure rate of 0.68% (0.17–2.71).

  4. MIRENA contains a total of 52 mg levonorgestrel. The in vivo levonorgestrel release rate 24 days after insertion is approximately 21 mcg per day, decreasing continuously to approximately 19 mcg per day after 1 year, to 11 mcg per day after 5 years and to 7 mcg per day after 8 years of use (see Table 7).

  5. Mirena ® (levonorgestrel-releasing intrauterine system) 52 mg is indicated for prevention of pregnancy for up to 8 years; replace after the end of the eighth year. Mirena is indicated for the treatment of heavy menstrual bleeding for up to 5 years in women who choose to use intrauterine contraception as their method of contraception; replace ...

  6. Heavy Menstrual Bleeding. Liletta, Mirena only. Indicated for heavy menstrual bleeding for up to 5 years in women who choose to use intrauterine contraception as a method of contraception. Initial...

  7. 2.1 Dosing Over Time Mirena contains 52 mg of levonorgestrel (LNG) released in vivo, at a rate of approximately 21 mcg/day after 24 days. This rate decreases progressively to approximately 11 mcg/day after 5 years and 7 mcg/day after 8 years.

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