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Very often we evaluate individuals who are told they have chronic ischemic white matter changes - punctate lesions - white matter hyperintensities - white ma...
White matter disease is a spectrum that can appear on MRI as mild to severe. Symptoms associated with it can range from nonexistent to severe. Because of this, the prognosis (outlook) for white matter disease varies from person to person.
13 maj 2019 · In the Mild Stroke Study-2 (MSS-2) of 190 patients with lacunar or mild cortical ischaemic stroke, 35 71 (37%) had some degree of white matter hyperintensity decline over 1 year.
30 sty 2024 · The life expectancy of a person with white matter disease depends on many factors, including the specific type, the rate at which it progresses, and the complications it causes.
Juvenile and adult (late) forms of the disease have a milder, more varied phenotype, a slower rate of progression and a significantly longer lifespan (although we have observed a rapid deterioration over a year in one case).
22 lis 2019 · CADASIL (Cerebral Autosomal Dominant Arteriopathy With Ischemic Leukoencephalopathy) and other monogenic hereditary cSVDs offer the opportunity for more specific diagnosis and earlier stage intervention (eg, in asymptomatic mutation carriers), but their molecular pathophysiology differs from acquired arteriosclerotic disease.
This retrospective study aims to describe the cellular changes (using immunohistochemical studies) in a spectrum of ischemic leukoencephalopathy. Methods: We studied 24 white matter ischemic injury cases with a well-documented interval from the ischemic event of interest.
