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Patients with a history of immunosuppression should be tested for progressive multifocal leukoencephalopathy by cerebrospinal fluid (CSF) examination for the presence of JC virus. A high index of suspicion should remain for neoplasia, including primary central nervous system (CNS) lymphoma and gliomatosis cerebri.
22 lis 2019 · Given the success in preventing stroke in general, with important reductions in incidence and mortality, are new treatments to target cSVD progression even necessary? That they are is supported by the evidence that many patients with cSVD experience progression with cognitive and functional decline despite conventional stroke risk reduction.
30 sty 2024 · Specific forms of white matter disease, such as MS or progressive multifocal leukoencephalopathy, may require other treatments. Those who have issues with balance and walking as a result of white...
28 sie 2021 · The Fazekas scale divides white matter into periventricular and deep white matter, and each region is scored based on the size of the lesions. The deep white matter component score, which identifies ischemia in small vessels, is useful in the assessment of patients with possible dementia (eg, Fazekas grade 2).
21 lut 2024 · A quarter of ischaemic strokes are lacunar subtype, typically neurologically mild, usually resulting from intrinsic cerebral small vessel pathology, with risk factor profiles and outcome rates differing from other stroke subtypes.
23 mar 2024 · The Fazekas scale is used to simply quantify the amount of white matter T2 hyperintense lesions usually attributed to chronic small vessel ischaemia, although clearly, not all such lesions are due to this.
Enhancing weight loss after ischemic stroke or TIA may help improve functional outcome and reduce risk for future vascular events, but clinical trials are needed to test and confirm these potential benefits.