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Patients with a history of immunosuppression should be tested for progressive multifocal leukoencephalopathy by cerebrospinal fluid (CSF) examination for the presence of JC virus. A high index of suspicion should remain for neoplasia, including primary central nervous system (CNS) lymphoma and gliomatosis cerebri.
28 sie 2021 · The Fazekas scale divides white matter into periventricular and deep white matter, and each region is scored based on the size of the lesions. The deep white matter component score, which identifies ischemia in small vessels, is useful in the assessment of patients with possible dementia (eg, Fazekas grade 2).
23 mar 2024 · The Fazekas scale is used to simply quantify the amount of white matter T2 hyperintense lesions usually attributed to chronic small vessel ischemia, although clearly, not all such lesions are due to this.
Grading: Fazekas grade I, Mild: few small punctate lesions in the white matter. Fazekas grade II, Moderate: larger white matter lesions that are beginning to become confluent.
Specific forms of white matter disease, such as MS or progressive multifocal leukoencephalopathy, may require other treatments. Those who have issues with balance and walking as a result of white...
13 maj 2019 · Most small vessel disease is sporadic, perhaps related to hypertension or other vascular risk factors, but a small proportion is due to rare genetic variants, of which the commonest is cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
28 paź 2022 · The GCS has three components to assess; eye opening – which can be graded from 1 point to 4 points, verbal response from 1 point to 5 points, and motor responsiveness from 1 point to 6 points. The sum of each component is used to calculate an overall score.
