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Polyneuropathy, meaning many abnormalities of the nervous system, is marked by clinical signs that include progressive weakness in the limbs, exercise intolerance, high-steppage, change in bark pitch and difficulty breathing.
Chronic inflammatory demyelinating polyneuropathy is a fairly common disorder in adult dogs and cats. The cause is unknown. Onset of tetraparesis with hyporeflexia is insidious and sometimes accompanied by cranial nerve dysfunction. Electromyography is usually normal, but nerve conduction velocities are slowed with temporal dispersion.
Signs and symptoms. Affected dogs often have megaesophagus leading to regurgitation and a quiet or silent bark. Other signs that are inconsistent between affected dogs include delayed reflexes in the limbs, muscle tremors, delayed ocular reflexes, exercise intolerance, and seizures. Signs first develop between 3-18 months of age.
Chronic inflammatory demyelinating polyneuropathy causes gradual weakness of all limbs, with decreased reflexes. The cranial nerves are sometimes also affected. It is fairly common in dogs, but the cause is unknown. Signs can improve with the use of corticosteroids but sometimes return once medications are stopped.
5 wrz 2024 · Each disease that causes neuropathy will have different clinical signs, prognoses, and treatments. Using this article’s explanation of nerves and neuropathies and your vet’s individualized ...
Symptoms may vary depending on the underlying condition and the severity of the disorder: Muscle tremors; Atrophy of the muscles; Weak reflexes; Lameness; Abnormal gait; Unable to climb stairs; Tires easily; Lack of coordination; Weight gain; Increased thirst
Clinical signs consist of voice change, laryngeal stridor, and a dry cough. In severe cases, exercise intolerance and episodes of respiratory—especially inspiratory—distress and cyanosis occur. Some affected animals have signs of a more generalized polyneuropathy, such as weakness and proprioceptive deficits.
