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While moving through its set region, if the microglial cell finds any foreign material, damaged cells, apoptotic cells, neurofibrillary tangles, DNA fragments, or plaques it will activate and phagocytose the material or cell.
21 mar 2024 · Microglial cells, as their name implies, are the smallest type of glial cells. Under a microscope, their small and elongated nuclei have a dash-like form, making them easily distinguishable from the larger and rounded nuclei of other cell types.
Microglial cells are the predominant parenchymal immune cell of the brain. Recent evidence suggests that like peripheral immune cells, microglia patrol the brain in health and disease.
1 paź 2021 · Microglia are an essential population of resident immune cells in the central nervous system (CNS) and retina. These microscopic cells possess sub-cellular processes that make them challenging to image due to limited resolution and contrast.
12 cze 2019 · Microglia play a central role in modulating synaptic structure and physiology, learning and memory processes. They exhibit morphological changes to perform these roles, therefore the...
8 maj 2017 · This microglial reactivity is a complex multistage activation process, which broadly encompasses their transformation from a ramified to an amoeboid morphology by first retracting the microglia...
19 mar 2016 · Microglia simultaneously regulate the programmed cell death and survival of developing neurons. Microglia promote differentiation and provide trophic support for developing astrocytes, oligodendrocytes, and vasculature.
