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25 paź 2022 · This ESMO Clinical Practice Guideline provides key recommendations for managing metastatic colorectal cancer. •. It covers clinical and pathological diagnosis, staging and risk assessment, treatment and follow-up. •. Treatment algorithms for locoregional, advanced/metastatic and recurrent advanced colorectal cancer are provided. •.
Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up † Originally published in 2018 – Ann Oncol (2018) 29(Suppl 4): iv192–iv237
1 dzień temu · Combination regorafenib, ipilimumab, and nivolumab (RIN) was evaluated in a phase 1 nonrandomized study (NCT04362839) of refractory microsatellite stable (MSS) metastatic colorectal cancer. Promising antitumor activity was previously reported in the non-liver metastatic (NLM) population. This updated analysis describes long-term survival outcomes in the NLM cohort and highlights durable ...
19 paź 2021 · General principles. Metastatic breast cancer (MBC) is an incurable disease, but survival improvements have been reported with appropriate therapeutic strategies. 1-8 Systemic therapy is the standard-of-care in MBC but may be supplemented with locoregional treatments (LRTs) according to the disease status of the individual patient.
This ESMO Clinical Practice Guideline provides key recommendations and algorithms for managing metastatic breast cancer. It covers diagnosis, staging, risk assessment, treatment, disease monitoring, palliative care and the patient perspective.
13 kwi 2023 · Metastasis is the most lethal manifestation of cancer, but our understanding of its biology and how to effectively treat it is rapidly advancing. This review highlights established and emerging principles of metastasis and provides a framework to develop more effective therapies for metastatic cancer.
6 paź 2020 · Metastatic dissemination occurs very early in the malignant progression of a cancer but the clinical manifestation of metastases often takes years. In recent decades, 5-year survival of...
