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30 cze 2021 · Despite the significant development of targeted therapy that has brought major benefits in the prognosis of cutaneous melanoma, vulvar and vaginal melanoma have a low response to these therapies due to the presence of different mutagenic profiles.
1 paź 2024 · Survival in vulvar melanoma is superior to that of vaginal melanoma. Most patients disease free five years after surgical resection received an adjuvant therapy. Complete response to treatment of recurrence or progression was most frequent with nivolumab plus ipilimumab.
29 wrz 2023 · Vulvar mucosal melanoma is a rare cancer that begins in the vulva. It can cause vulvar lumps, itchiness, bleeding, and unusual discharge.
15 maj 2014 · Surgery is the preferred primary treatment for vulvovaginal melanoma, if feasible, and not requiring an exenterative procedure. The two main considerations in surgery are the management of the primary tumor and nodal assessment and management.
The main treatment for vaginal or vulvar mucosal melanoma is surgery. This is often in a specialised centre, and there should be support from an experienced cancer team. There are a number of different approaches to surgery for vaginal and vulvar mucosal melanoma, depending on its location and how advanced it is.
14 cze 2021 · While the mortality rate of cutaneous melanoma has dropped by 7% annually during the last 5 years, the prognosis of vulvar melanoma remains dismal: the 5-year overall survival rate is 47% compared with 92% for cutaneous melanoma.
Materials/Methods From the Surveillance, Epidemiology, and End Result registry, 201 patients with vaginal melanoma were identified. Patients’ characteristics and prognostic factors including age, race, extent of surgery, and use of radiation therapy were obtained.
