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30 cze 2021 · Due to the poorly associated prognosis determined mainly by the discovery of melanoma in advanced stages, melanoma remains the skin cancer with the highest mortality, the 5-year survival rate being less than 80% and depending on the degree of local tumor extension, lymphatic invasion, and presence of metastases [9,10].
1 gru 2020 · WLE with adequate margins is the mainstay treatment for early-stage vulvar melanoma while complete resection of the primary tumor is the standard treatment for early-stage vaginal melanoma. SLNB is the major treatment for vulvar melanoma, but its efficacy in vaginal melanoma remains to be defined.
25 paź 2022 · Vulvar melanoma (VM) is a rare and fatal disease. Knowledge of this disease is poor and, consequently, so is knowledge of the prognosis. Our aim was to collect evidence on VM with particular attention to its molecular profile and related clinical and therapeutic implications.
20 paź 2021 · Vaginal melanoma has a very poor prognosis, with a five-year overall survival of 15%. 51 In a 2017 systematic review of 805 cases reported over the last 20 years (mostly case reports), the mean recurrence-free survival was short, at 16 months, with a mean overall survival of only 22 months. 52
1 paź 2024 · Survival in vulvar melanoma is superior to that of vaginal melanoma. •. Most patients disease free five years after surgical resection received an adjuvant therapy. •. Complete response to treatment of recurrence or progression was most frequent with nivolumab plus ipilimumab. •.
15 maj 2014 · Surgery is the preferred primary treatment for vulvovaginal melanoma, if feasible, and not requiring an exenterative procedure. The two main considerations in surgery are the management of the primary tumor and nodal assessment and management.
2 sie 2021 · Primary vaginal melanoma typically has a worse prognosis than other histological subtypes with overall 5-year survival between 15%` and 20% [4, 48, 54]. Complete surgical excision is typically the treatment of choice, although resection is difficult to achieve negative margins [ 54 ].
