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  1. 9 wrz 2021 · As skin color by melanin determines the identity of an individual in the given socio-cultural context, disorders of pigmentation can lead to significant psychosocial consequences.

  2. 21 cze 2023 · Skin pigmentation is the most variable human characteristic that can be observed and has been used throughout history to classify humans into distinct groups. Many factors influence skin colour, but the melanin pigment is considered the most important because its type and quantity can determine variations in pigmentation shades.

  3. Melanins and melanogenesis: Elucidating chemical and physical properties is central to unravel biological roles and functions and to translate clues from pigment cells to innovative applications.

  4. 15 gru 2020 · Melanocytes are pigment-producing cells, and their key regulating transcription factor is the melanocyte-specific microphthalmia-associated transcription factor (m-MITF). Ultraviolet (UV) radiation is a unique modulator of skin pigmentation influencing tanning pathways.

  5. 28 wrz 2023 · Melanin is a pigment mostly known for absorbing the genetically-damaging ultraviolet (UV) radiation from the sun and releasing it as heat and is part of the immune system. Typically dark in color (eumelanin and neuromelanin), neuromelanin increases as individuals age (4), but significant loss is seen in individuals with AD, PD, and LBD (5 – 7).

  6. Excessive or deficient amounts of melanin cause disorders showing abnormal skin pigmentation. Although wrinkling and laxity are well-identified symptoms [1], abnormal pigmentation is also a common symptom in aging skin [2, 3, 4, 5].

  7. 22 lut 2023 · In this review, we focus on the recent advances in the research of melanin in all aspects. Firstly, the classification, source, and degradation of melanin are summarized. Secondly, a detailed description of the structure, characterization, and properties of melanin is followed.