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24 maj 2011 · Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs.
- Evaluating Cinchona bark and quinine for treating and preventing ...
In this paper, we consider methods used from the 17th to the...
- Evaluating Cinchona bark and quinine for treating and preventing ...
Quinine is bacteriostatic, highly active in vitro against protozoa, and inhibits the fermentation of yeast.11. Quinine and quinidine have cardiodepressant activity. The latter compound is used for its antiarrhythmic activity.
Quinine is a medication used to treat malaria and babesiosis. [5] This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available. [5] [6] While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. [5]
Quinine is used parenterally to treat life-threatening infections caused by chloroquine-resistant Plasmodium falciparum malaria. Quinine acts as a blood schizonticide although it also has gametocytocidal activity against P. vivax and P. malariae. Because it is a weak base, it is concentrated in the food vacuoles of P. falciparum.
1 lut 2024 · Plasmodium falciparum is a parasite that gets into the red blood cells in the body and causes malaria. Quinine works by killing the parasite or preventing it from growing. This medicine may be used alone or given together with one or more medicines for malaria.
20 sty 2017 · In this paper, we consider methods used from the 17th to the 21st centuries to assess the effects of Cinchona bark and of quinine and its derivatives for (i) treating and (ii) preventing malaria in individuals and (iii) in attempts to control malaria in populations.
Cinchona bark contains a chemical called quinine. Quinine has effects that help fight malaria and reduce heart palpitations. People use cinchona for cancer, hemorrhoids, malaria, muscle...
