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15 lis 2020 · We searched up to February 2020 for well‐designed trials that compared any medicine used for treating sleep problems in people with dementia with a fake medicine (placebo). We consulted a panel of carers to help us identify the most important outcomes to look for in the trials.
- Sleep disturbances in dementia: What they are and what to do
Typical presentations of sleep disturbances in persons with...
- Sleep disturbances in dementia: What they are and what to do
We found nine trials (649 participants) investigating four types of medicine: melatonin (five trials), trazodone (one trial), ramelteon (one trial), and orexin antagonists (two trials). Participants in all the trials had dementia due to Alzheimer's disease.
Medications for the underlying dementia as well as medications for co-morbid conditions (e.g. β2 agonist inhalers for pulmonary disease, anti-hypertensive medications) may contribute to sleep disturbance.
4 wrz 2024 · Tailored, clinically effective interventions that consider the presence of Alzheimer’s disease biomarkers, such as amyloid, tau, cerebrovascular disease, or alpha-synuclein in key sleep-related circuits, are essential to developing feasible, cost-effective, and scalable treatments for older adults with or without cognitive impairment.
Typical presentations of sleep disturbances in persons with dementia are described, along with medications that may interfere with sleep, and suggestions for nursing measures that can be implemented to enhance sleep are presented.
29 maj 2019 · Numerous factors can affect sleep, including medications, living environment and physical, mental and psychosocial factors (e.g. loneliness and stress). Sleep architecture changes with aging, with less deep sleep (slow wave sleep) and an increased frequency of awakenings after sleep onset.
Dementia medications. One study investigated whether donepezil 5 mg daily for 14 weeks could help to alleviate sleep disturbances (assessed using actigraphy) and sleep symptoms such as dream enactment in 16 people with DLB . Eight patients had sleep disturbances at baseline.
