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The MDRD GFR Equation estimates glomerular filtration rate based on creatinine and patient characteristics.
The glomerular filtration rate is the flow rate of filtered fluid through the kidney. The creatinine clearance rate (CCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR.
The MDRD equation (from the Modification of Diet in Renal Disease trial) is used to estimate glomerular filtration rate in chronic kidney failure.
The MDRD calculator is based on the Modification of Diet in Renal Disease formula and estimates the glomerular filtration rate by taking into account serum creatinine and other patient data (age, gender and race).
MDRD 4-variable GFR Equation. GFR in mL/min per 1.73 m 2 = 175 x SerumCr -1.154 x age -0.203 x 1.212 (if patient is black) x 0.742 (if female) Notes: The original Modification of Diet in Renal Disease (MDRD) equation was based on 6 variables: age, sex, ethnicity, serum creatinine, urea, and albumin (often referred to as MDRD 6).
Accurately estimate Glomerular Filtration Rate (eGFR) using the Abbreviated MDRD Study Equation (SI units). eGFR estimates kidney function using the MDRD equation, based on serum creatinine, age, gender, and race.
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