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15 sie 2024 · Detailed dosage guidelines and administration information for Vicodin (hydrocodone bitartrate and acetaminophen). Includes dose adjustments, warnings and precautions.
The below tables are an approximate guide only. Opiate bioavailability and response are highly variable. Wide inter-patient variation exists. Consider the need to adjust dose for conditions that increase opiate risk (eg elderly, co-morbidities, renal or hepatic impairment).
500 – 999 mg 15 : 1 6.6% > 1,000 mg 20 : 1 5% Example of conversion to oral methadone: 1. ®Patient is taking 80 mg OxyContin orally 3 times daily. 2. The total daily dose of oxycodone is 240 mg daily. 3. The next step is to convert 240 mg of oral oxycodone to the daily oral morphine equivalent dose (DOMED). 4.
Medscape - Indication-specific dosing for Vicodin, Lorcet, Hycet, Norco, Lortab Elixir, Anexsia, Vicodin ES, Vicodin HP, Xodol, Zamicet (hydrocodone, acetaminophen), frequency-based adverse...
A dose reduction of at least 50% is recommended when switching at high doses (eg, oral morphine or equivalent doses of 500mg/24 hours or more), in elderly or frail patients, or because of intolerable undesirable effects.
This opioid dose equivalence table is intended for comparison of different opioid and opioid formulations in individual patients or in patient cohorts. Caution is required if opioid dose equivalence tables are used to guide opioid switching, as the administration of a calculated ‘equivalent’ dose of the replacement opioid may lead to overdosage.
Opioid Conversion Tables Ernest Dole, Pharm.D., BCPS, PhC, FASHP Clinical Pharmacist, University of New Mexico Hospitals Chronic Pain Consultation & Treatment Center
