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  1. The recommended therapeutic range for the INR (which is calculated from the patient's PT, a mean control PT, and the international sensitivity index) for oral anticoagulant treatment of most conditions is 2.0 to 3.0. In patients with mechanical cardiac valves, the INR should be at least 2.5 to 3.5.

  2. 30 lis 2022 · In healthy people an INR of 1.1 or below is considered normal. An INR range of 2.0 to 3.0 is generally an effective therapeutic range for people taking warfarin for certain disorders. These disorders include atrial fibrillation or a blood clot in the leg or lung.

  3. 8 cze 2024 · INR is a standardized measure of PT, ensuring consistency in results across different laboratories. The normal range for INR is around 0.8 to 1.2. Higher INR values suggest a slower clotting time and an increased risk of bleeding.

  4. The INR is a mathematical conversion of a patient's PT that accounts for the sensitivity of the thromboplastin used in a given laboratory by factoring in the international sensitivity index (ISI) value supplied by its manufacturer. The INR is calculated as follows: INR = (patient PT/MNPT) ISI, in which MNPT is the geometric mean of the PT of at ...

  5. A Critical Value / Critical Result is defined as: A value/result that represents a pathophysiological state at such variance with normal (expected values) as to be life-threatening unless something is done promptly and for which some corrective action could be taken.

  6. In the thorough review of the use of the international normalized ratio (INR) for monitoring anticoagulation with orally administered anticoagulant therapy, which was published in the September 1993 issue of the Mayo Clinic Proceedings (pages 897 to 898), Drs. Nichols and Bowie provided two tables of recommended INR ranges.

  7. 20 lis 2015 · Anticoagulant therapy with warfarin with a goal INR of 2 to 3 is effective in treating tissue valve thrombosis in most patients. Cardiac valve replacement and the risk of thrombosis are increasingly common in aging populations.

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