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The primary goal of treatment is to achieve disease remission or quiescence, defined by minimal symptoms, low levels of autoimmune inflammatory markers, and minimal systemic glucocorticoid requirement while the patient is treated with maintenance doses of immunomodulatory or immunosuppressive medications.
21 paź 2022 · In clinical trials, voclosporin has been shown to be effective in treating lupus. Other potential drugs to treat lupus are currently being studied, including abatacept (Orencia), anifrolumab and others.
Antimalarial agents are the first-line therapy for all types of cutaneous lupus erythematosus. A clinical effect may be seen as early 2 weeks; if there is no change in 12 weeks, therapy should be escalated. Combination therapy of 2 antimalarial agents (HCQ + CQ) or quinacrine can be tried first.
7 maj 2024 · Treatment goals include reducing disease exacerbations, hospitalizations, and organ damage due to the disease or treatment toxicity. Hydroxychloroquine is standard of care for SLE and has been associated with a significant reduction in mortality.
matism have published guidelines for the eval-uation and management of patients with SLE and of lupus nephritis. TREATMENT PRINCIPLES Key Points d Treatment decisions are often based on the type and severity of organ involvement. d There is a paucity of clinical trials and evidence-based recommendations for the treatment of many of the lupus ...
The recent updates on treatment recommendations for the management of systemic lupus erythematous have provided greater clarity in the way existing anti-inflammatory and immunomodulatory drugs are used, in treating disease activity, preventing flares, and reducing irreversible organ damage and toxicity arising from the treatments themselves.
3 lut 2020 · Systemic lupus erythematosus (SLE) is a chronic, multiorgan, systemic autoimmune disease that is more common in women than men and is typically diagnosed during reproductive age, necessitating sex-specific considerations in care.
