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  1. www.mdpi.com › 2077/0383/13-8 › 2419The Spectrum of Cutaneous Manifestations in Lupus Erythematosus:...

    21 kwi 2024 · Lupus erythematosus (LE) is an autoimmune inflammatory disease with complex etiology. LE may present as a systemic disorder affecting multiple organs or be limited solely to the skin. Cutaneous LE (CLE) manifests with a wide range of skin lesions divided into acute, subacute and chronic subtypes.

  2. pubmed.ncbi.nlm.nih.gov › 38673692The Spectrum of Cutaneous Manifestations in Lupus Erythematosus:...

    21 kwi 2024 · Cutaneous LE (CLE) manifests with a wide range of skin lesions divided into acute, subacute and chronic subtypes. Despite classic forms of CLE, such as malar rash or discoid LE, little-known variants may occur, for instance hypertrophic LE, chilblain LE and lupus panniculitis.

  3. www.ncbi.nlm.nih.gov › pmc › articlesCutaneous Lupus Erythematosus: Progress and Challenges

    4 kwi 2020 · Recent Findings. Diagnostic challenges exist in better defining CLE as an independent disease distinct from systemic lupus erythematosus with cutaneous features and further classifying CLE based on clinical, histological, and laboratory features.

  4. onlinelibrary.wiley.com › doi › fullAn update on clinical trials for cutaneous lupus erythematosus

    15 mar 2024 · Cutaneous lupus erythematosus (CLE) is an autoimmune skin disease with dermatologic manifestations that can occur with or without systemic lupus erythematosus (SLE). CLE lesions typically involve sun-exposed areas secondary to photosensitivity.

  5. onlinelibrary.wiley.com › doi › 10British Association of Dermatologists guidelines for the...

    25 cze 2021 · The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the management of cutaneous lupus erythematosus (CLE) in the presence or absence of systemic lupus erythematosus (SLE) in adults, young people and children.

  6. www.ncbi.nlm.nih.gov › pmc › articlesDiagnosis and Management of Cutaneous Manifestations of...

    26 paź 2022 · Acute cutaneous lupus erythematosus (ACLE) characterized by violaceous to erythematous patches and thin plaques involving the malar cheeks. Importantly, this pathognomonic “butterfly rash” of lupus strikingly spares the nasolabial folds helping to distinguish ACLE from disease mimics.

  7. link.springer.com › article › 10Cutaneous Lupus Erythematosus: An Update on Pathogenesis and...

    4 maj 2023 · Cutaneous lupus erythematosus comprises a variety of clinical manifestations and displays interindividual heterogeneity. Keratinocytes, cytotoxic T lymphocytes and plasmacytoid dendritic cells establish a self-perpetuating interplay between the innate and adaptive immune system in lesional skin, which is orchestrated by type I interferons (IFNs).