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1 lip 2021 · Lupus erythematosus (LE) is one of the most common connective tissue diseases present worldwide and affecting all age groups, genders and ethnicities. 1 Cutaneous manifestations are common in LE, and accurate diagnosis and subclassification of the disease is key to the appropriate clinical management of these patients.
21 kwi 2024 · Lupus erythematosus (LE) is an autoimmune inflammatory disease with complex etiology. LE may present as a systemic disorder affecting multiple organs or be limited solely to the skin. Cutaneous...
21 kwi 2024 · The Mayo Clinic diagnostic criteria are used to confirm the diagnosis and presence of two from three major criteria (erythematous skin lesions caused by exposure to cold, acral location, presence of skin lesions characteristic to lupus erythematosus), and at least two from three minor criteria (coexistence with SLE or CLE, improvement after ...
Serologic testing may reveal the presence of antibodies directed against double-stranded DNA (anti-dsDNA), Smith antigen (anti-Smith), U1 ribonucleoprotein (anti-U1RNP) and/or anti-Ro antibodies. In the vast majority of cases, the lupus band test, which is a DIF technique, is positive.
Lupus erythematosus (LE) is a prototype of connective tissue disease with a variety of cutaneous and sys- temic manifestations.
The Cutaneous Lupus Area Severity Index (CLASI) is a validated tool to measure activity and damage both in clinical trials but also for the clinician to evaluate treatment and follow the course of the disease among patients. CLE is known to have substantial impact on the life of those affected.
1 maj 2023 · This review proposes to discuss the main etiopathogenic, clinical, diagnostic and therapeutic aspects of cutaneous lupus erythematosus, aiming to update internists and specialists from different areas.
