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The MCHC is classically determined by the equation: MCHC = (HGB/HCT) x 100. In automated equipment, however, the HCT is a calculated value based on the RBC and the MCV values which are directly measured parameters.
Explanation: The red cell MCV is measured directly on cell counters; this is true whatever method is employed to enumerate cells. The counter is able to plot a red cell volume histogram, and the mean is determined. MCV can be calculated from the spun hematocrit as in option b.
23 sie 2024 · A low MCHC indicates a low concentration of hemoglobin in your red blood cells, often as a result of iron deficiency or diseases that affect hemoglobin production. A high MCHC indicates a higher hemoglobin concentration in red blood cells than what is normal.
Sometimes a set of spurious values may be the first clue to an otherwise unsuspected clinical condition (e.g., the combination of low hematocrit, normal hemoglobin, and high MCV and MCHC is characteristic of cold agglutinins).
27 lip 2024 · The mean corpuscular volume (MCV) is a critical measurement for identifying the underlying cause of anemia. MCV is a laboratory value that measures the average size and volume of red blood cells (RBCs), providing essential information in the diagnostic process for anemia. MCV is expressed as femtoliters (fL).
Iron deficiency is classically associated with microcytic hypochro-mic anaemia, but low MCV, MCH or MCHC can be seen in other conditions, notably the thalassaemias.
13 wrz 2024 · Low and high MCV values can mean any number of things: It's important to note that a person can have anemia and have a normal MCV. This is called normocytic anemia .