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13 mar 2023 · Specifically, elevated red blood cell distribution width (RDW), lower mean corpuscular hemoglobin concentration (MCHC), and Hb levels are associated with increased disease severity and lower survival rates in patients with COPD [8-10].
Low concentrations of hemoglobin have previously been demonstrated in many patients with COPD. There is evidence of anemia as a prognostic factor in acute exacerbations, but the detailed relationship between concentrations of hemoglobin and mortality is not known.
14 mar 2011 · Hypoxemia in patients with COPD: cause, effects, and disease progression. Chronic obstructive pulmonary disease (COPD) is a leading cause of death and disability internationally. Alveolar hypoxia and consequent hypoxemia increase in prevalence as disease severity increases.
PDF. Abstract. Haemoglobin (Hb) abnormalities in chronic obstructive pulmonary disease (COPD) are not well characterised. The present authors investigated the prevalence and association of abnormal Hb with clinical outcomes.
In conclusion, low concentrations of hemoglobin are frequent in COPD patients with acute exacerbations, and predict long-term mortality. Keywords: pulmonary disease, chronic obstructive, anemia, mortality, polycythemia,
In COPD, anaemia is associated with increased morbidity, but the relationship between haemoglobin over its entire observed range and morbidity is poorly understood. Such an understanding could guide future therapeutic targeting of haemoglobin in COPD management.
A low hemoglobin level stimulates alveolar ventilation and may thus be responsible for the low Paco 2 level. Transfusion by increasing the hemoglobin level may suppress ventilation and cause hypercapnia.
