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1 lis 2016 · In clinical practice, insomnia and anxiety are the most common reasons for physicians to prescribe benzodiazepines to older adults. 3,7,8 Most studies on benzodiazepine effects for these 2 indications were conducted in nonelderly patients, and long-term follow-up evaluating long-term efficacy is lacking. 9 In young adults, a short course of ...
12 sty 2015 · Long-term use can lead to dependence and withdrawal symptoms when discontinued. Benzodiazepines can impair cognition, mobility, and driving skills in older people, as well as increase the risk of falls.
1 mar 2024 · At first glance, this effect seems reasonable given BZRAs’ sedating effects in the elderly, possibly causing falls and fractures. The initial landmark case-control study of the effects of BZRAs on hip fracture rates that started the modern field of pharmacoepidemiology is a case in point ( 7 ).
recognize the risks associated with (long-term) benzodiazepine use, and (3) initiate/manage a benzodiazepine taper and name several alternatives to benzodiazepines for treating insomnia and anxiety in older adults.
In the present study, we examined the effects of a single acute dose of lorazepam in elderly long-term users treated with this drug for anxiety and related conditions. Memory and psychomotor performance was assessed and self-report measures of mood states and anxiety levels were obtained.
She has been taking lorazepam (1 mg nightly) since the death of her husband 12 years ago. Recent research about chronic benzodiazepine therapy leading to an increased risk of Alzheimer disease prompts a discussion about benzodiazepine cessation. 1
13 gru 2017 · This study presents an updated meta-analysis of the effects of benzodiazepines on cognitive functioning in long-term, current users of these agents, those who have recently withdrawn and on those who have successfully abstained following withdrawal.
