Search results
29 wrz 2022 · Key issues in COGs for cell-based manufacturing include direct costs (e.g., staff, materials services), indirect costs of organization overheads, non-recurring costs (e.g., facility...
1 lip 2020 · This figure outlines high-level steps to calculate an aggregate per batch manufacturing cost as well as step- and category-specific costs. To start CBT costing, the manufacturing process of an individual product is categorized in mutually exclusive steps 1 to 3.
30 paź 2020 · This study demonstrates the feasibility of retrospectively estimating the cost of manufacturing development of two cell-based therapies using a CBT manufacturing cost framework. The original framework was designed and validated for use in small-scale routine manufacturing of cell-based therapies.
20 maj 2020 · This framework and methodology provide step-by-step guidance to estimate manufacturing costs specifically for cell-based therapies manufactured in academic and other small-scale enterprises. The framework and methodology can be used to inform and plan cost-conscious strategies for CBTs.
The aim of this study was to use a recently published cost-based pricing model to calculate prices for cell and gene therapies, with OTL-200 and AVXS-101 as case study examples. Methods: Using the pricing model proposed by Uyl-de Groot and Löwenberg, we estimated a price for both therapies.
1 gru 2022 · The aim of this study was to use a recently published cost-based pricing model to calculate prices for cell and gene therapies, with OTL-200 and AVXS-101 as case study examples.
2 sty 2023 · Advanced gene and cellular therapies risk a second “valley of death” due to their high costs and low patient population. As these are life‐saving therapies, measures are urgently needed to prevent ...
