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1 gru 2018 · Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely aggressive malignancy associated with a poor overall prognosis. Women affected may vary in age, but are most often diagnosed in their perimenopausal years.
1 kwi 2017 · We present refined prognostic estimates of survival associated with risk factors among women with uterine leiomyosarcoma. Our results support the conclusion that early and complete surgical resection remains the best-evidenced effective treatment for uterine leiomyosarcoma.
While the majority of women present with disease confined to the uterus, about 30% to 35% will present with metastatic disease and have a poor prognosis (Roberts et al., 2018).
Uterine leiomyosarcoma is challenging to diagnose preoperatively. It can mimic the appearance of benign uterine leiomyomas, otherwise known as a fibroid, and can present with heavy menstrual bleeding, pelvic pain and a palpable mass.
29 gru 2022 · Leiomyoma is one of the most frequent benign tumors in the reproductive age group, with an estimated prevalence of 40–50% in women older than 35 years [ 1, 2 ]. However, the reported incidence in the postmenopausal age group is as low as 1–2% in the 60–80 year age group [ 3 ].
Chemotherapy increases survival of women with metastatic leiomyosarcoma. Early and complete resection is the best-evidenced treatment for uterine leiomyosarcoma. Oophorectomy and lymphadenectomy may be safely omitted for clinically uterus-confined leiomyosarcoma.
broad ligament and uterus. The malignant transformation of uterine leiomyomas is more likely to occur in women ranging in age from 40 73 years. However, the prognosis for patients diagnosed with uterine LMS arising from preexisting leiomyo - mas is better than for patients diagnosed with primary uterine LMS (Yanai et al., 2010). Uterine ...