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  1. 15 wrz 2022 · A commonly accepted paradigm (based on Virchow’s triad of thrombogenesis) posits the pathogenesis of LV thrombus as occurring as a result of the interplay of 3 factors: (1) stasis attributable to reduced ventricular function, (2) endocardial injury, and (3) inflammation/hypercoagulability (Figure 1).

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  2. 23 wrz 2022 · If OAC is initiated, a treatment duration might be 13 months, depending on bleeding risk. On the basis of reasonable data and evidence, post-MI patients with LV thrombus should be treated with OAC, typically for a duration of 3 months.

  3. 14 wrz 2022 · We suggest that, on the basis of limited data, patients with NICM with LV thrombus should be treated with OAC for at least 3–6 mo, with dis-continuation if LVEF improves to >35% (assuming resolution of the LV thrombus) or if major bleeding occurs.

  4. Introduction Left ventricular thrombus (LVT) is a frequent complication of left ventricular systolic dysfunction (1). Incidence following acute myocardial infarction is estimated at 13–20% and up to 15% in with non-ischaemic cardiomyopathy (2, 3).

  5. Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies. AHA Guideline and Statements Hub content for Management of Patients at Risk for and with Left Ventricular Thrombus.

  6. Left ventricular (LV) thrombus is a feared complication of LV dysfunction associated with high rates of systemic embolism, morbidity, and mortality. Traditionally, LV thrombus has been associated with acute myocardial infarction (MI).

  7. The presence of a left ventricular thrombus in a patient with severe coronary artery disease poses a difficult clinical decision regarding safety, effectiveness, timing, and type of coronary revascularization.

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