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  1. 15 wrz 2022 · A commonly accepted paradigm (based on Virchow’s triad of thrombogenesis) posits the pathogenesis of LV thrombus as occurring as a result of the interplay of 3 factors: (1) stasis attributable to reduced ventricular function, (2) endocardial injury, and (3) inflammation/hypercoagulability (Figure 1).

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  2. 15 wrz 2022 · Left ventricular thrombus incidence and behavior studied by serial two-dimensional echocardiography in acute anterior myocardial infarction: left ventricular wall motion, systemic embolism and oral anticoagulation.

  3. Left ventricular (LV) thrombus is a feared complication of LV dysfunction associated with high rates of systemic embolism, morbidity, and mortality. Traditionally, LV thrombus has been associated with acute myocardial infarction (MI).

  4. Management of LV thrombus (LVT) is challenging and crucial to prevent the potential development of thromboembolic complications such as stroke. Anticoagulation with warfarin is recommended for the prevention of thromboembolic events, but novel oral anticoagulants (NOAC) have been used in clinical practice without supporting evidence.

  5. Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies. AHA Guideline and Statements Hub content for Management of Patients at Risk for and with Left Ventricular Thrombus.

  6. 27 cze 2023 · Left ventricular thrombus (LVT) is a well-known complication of acute MI (AMI) and non-ischaemic cardiomyopathies. 1 The presence of LVT increases the risk of embolic complications, such as stroke or systemic embolisation, hence treatment with oral anticoagulation is often indicated. 2 The European and American guidelines recommend a period of ...

  7. 23 wrz 2022 · On the basis of limited data, patients with nonischemic cardiomyopathy with LV thrombus should be treated with OAC for at least 36 months, with discontinuation if LV ejection fraction improves to >35% (assuming resolution of the LV thrombus) or if major bleeding occurs.