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9 maj 2023 · History of Animal Testing. Animals are used to develop medical treatments, determine the toxicity of medications, check the safety of products destined for human use, and other biomedical, commercial, and health care uses. Research on living animals has been practiced since at least 500 BC.
18 kwi 2021 · When Did Testing on Animals Begin? Animal dissection dates back as early as circa 500 BC. Scientists like Erasistratus, Herophilus, and Aristotle performed various experiments on animals to discover living organisms' functions. In ancient Rome and Alexandria, scientists practiced vivisection (dissection of a living organism) on human criminals.
The available data, however, suggest that the number of animals used in research and testing in the Western world peaked in the 1970s, and decreased until the late 1990s, or early 2000s, to about half the number of 30 years earlier, and stabilizing in recent years.
19 sie 2022 · The contemporary pharmaceutical industry is voicing growing concerns about the translatability and reproducibility of animal models. In addition, the usefulness of certain of the required regulatory safety tests in animals is being increasingly questioned.
Animal testing regulations are guidelines that permit and control the use of non-human animals for scientific experimentation. They vary greatly around the world, but most governments aim to control the number of times individual animals may be used; the overall numbers used; and the degree of pain that may be inflicted without anesthetic .
The future. Many research facilities are now ditching some animal tests, embracing non-animals technological advances and moving more quickly to human trials. The global non-animal testing market was valued at $9.8 billion in 2021 with significant further growth predicted by 2030.
21 paź 2020 · Here we present a mini-review on the development of animal testing, as well as on alternative in vitro and in silico methods, that may at least partly replace animal experiments in the near future.