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27 mar 2023 · Key outcome measures include frequency of migraines attacks and intensity of headache pain. Additional exploratory outcome measures include changes in photosensitivity, retinal vascular diameter, and blood biomarkers of vascular tone.
27 mar 2023 · The primary objective of the LARGE trial is to evaluate the effectiveness of oral supplementation of L-arginine, AGE or the combined treatment of oral L-arginine and AGE, in reducing the severity and frequency of migraine attacks in chronic frequent episodic migraines in adults.
27 mar 2023 · Accumulating evidence suggests that cerebral arteries dilate during migraine, causing distal microvessels to constrict, which could activate nociceptors and cause onset of headache pain. If so, preventing or attenuating chronic microvascular constriction, and promoting a dilatory phenotype, may reduce frequency and/or severity of migraines.
11 lis 2022 · The primary aim of the L-Arginine and Aged Garlic Extract (LARGE) trial is to investigate whether oral treatment with dietary nutraceuticals, L-arginine and aged garlic extract (AGE), both systemic vasodilatory agents, will alleviate migraine frequency, duration and severity in adults with chronic frequent episodic migraines.
Discover the connection between L-arginine and headaches. Learn about potential benefits and side effects of taking L-arginine for headache relief.
10 sie 2023 · What the research says. Research on the use of L-arginine for specific conditions shows: Angina. Studies suggest that L-arginine might decrease symptoms and improve quality of life in people with a mild to severe form of this type of chest pain. High blood pressure (hypertension).
27 mar 2023 · Accumulating evidence suggests that cerebral arteries dilate during migraine, causing distal microvessels to constrict, which could activate nociceptors and cause onset of headache pain.
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