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27 mar 2023 · The primary objective of the LARGE trial is to evaluate the effectiveness of oral supplementation of L-arginine, AGE or the combined treatment of oral L-arginine and AGE, in reducing the severity and frequency of migraine attacks in chronic frequent episodic migraines in adults.
27 mar 2023 · The primary aim of the L-Arginine and Aged Garlic Extract (LARGE) trial is to investigate whether oral treatment with dietary nutraceuticals, L-arginine and aged garlic extract (AGE), both systemic vasodilatory agents, will alleviate migraine frequency, duration and severity in adults with chronic frequent episodic migraines.
5 dni temu · Since L-arginine may be related to cardiovascular status, the researchers examined their results after exclusion of 12 people who had possible cardiovascular comorbidities, and 20 people who were taking blood pressure medication as a migraine preventative treatment.
22 paź 2021 · We evaluated the metabolism of arginine in a group of patients affected by chronic migraine. Quantification of arginine, ornithine, citrulline, monomethyl arginine (NMMA), dimethylarginines (ADMA, SDMA), and tyramine was performed by ultra-performance liquid chromatography coupled with a triple quadrupole mass spectrometer.
27 mar 2023 · A 74-year-old female subject with suboptimal management of episodic tension headache was treated with a daily dose of 1.5 g l-arginine and 1.2 g aged garlic extract (AGE).
Thus, this prospective study aimed to measure the serum concentrations of the NO substrate L-arginine, the NO synthase inhibitor asymmetric dimethylarginine (ADMA), and the L-arginine transport regulator symmetric dimethylarginine (SDMA) in migraine patients in a headache-free period.
27 lip 2021 · PACAP-38 was reported to have provoked a migraine-like headache in 73% of patients with migraine without aura, while VIP infusion caused migraine-like headache in only 18% of subjects. Examining the clinical data table, if one considered probable migraine then 32% of subjects were positive for VIP.
