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28 sie 2012 · The kidney has a pivotal role in controlling arterial blood pressure by regulating salt and water excretion and controlling peripheral vascular tone via several neurohormonal mechanisms.
24 sty 2023 · In the present review, we summarize the current overview on the molecular mechanisms for modulation of blood pressure associated with renal ion channels/transporters including NHE3, NKCC2,...
11 lut 2021 · The kidneys, which have a high specific metabolic rate, play an essential role in the long-term regulation of arterial blood pressure. In this review, we discuss the emerging role of renal...
In this setting, kidney plays a pivotal role on the modulation of blood pressure via extracellular fluid volume regulation acquired through salt reabsorption activity, under the control of the renin–angiotensin–aldosterone system (RAAS).
23 maj 2024 · In the kidney, SGLT2 functions by reabsorbing glucose from the nephron’s tubule into the bloodstream. SGLT2 inhibitors are medications that hinder the function of SGLT2, thus preventing the...
28 mar 2024 · Genetic and Epigenetic Mechanisms Regulating Blood Pressure and Kidney Dysfunction. The pioneering work of Dr Lewis K. Dahl established a relationship between kidney, salt, and high blood pressure (BP), which led to the major genetic-based experimental model of hypertension.
15 maj 2023 · Fluid overload secondary to loss of functional nephron mass can elevate blood pressure, which is characteristic of hypertension shown in chronic kidney disease (CKD). Therefore, it is logical to use diuretics at appropriate dose to lower blood pressure in patients with CKD and hypertension.
