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Learn how to interpret your SDMA results for cats and dogs. Follow this algorithm to determine if kidney disease is probable and what steps you should take.
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FIGURE 1. Curvilinear inverse relationship between serum creatinine (sCr) and glomerular fi ltration rate (GFR). Note that, on the right side of the graph, relatively large reductions in GFR result in only minor changes in sCr, while the opposite relationship is demonstrated at the top of the graph.
FIGURE 1. Curvilinear inverse relationship between serum creatinine (sCr) and glomerular filtration rate (GFR). Note that, on the right side of the graph, relatively large reductions in GFR result in only minor changes in sCr, while the opposite relationship is demonstrated at the top of the graph.
Results of both tests should be interpreted in light of patient’s hydration status. Urine specific gravity. UPC >0.5 in dogs; UPC >0.4 in cats. 0.6 0.7 1.0. Sept ’15 Oct ’15 Nov ’15. Urine protein to creatinine (UPC) ratio. <1.030. 1.030. 1.035. See www.iris-kidney.com for more detailed staging, therapeutic, and management guidelines.
2 sie 2019 · Results. For dogs in Group A1, renal disease was diagnosed in 9/9 dogs with a GFR ≥40% decreased below the mean GFR of their body weight category, in 5/6 dogs with a ≥30% but <40% reduction in GFR and in 7/9 dogs with a ≥20% but <30% reduction in GFR.
Determination of glomerular filtration rate (GFR) is considered crucial in the evaluation of companion animal (cat, dog) renal disease, because the GFR directly relates to the functional renal mass.
Glomerular filtration rate (GFR) is the gold standard measurement of renal function; however, its measurement is rarely indicated in patients with CKD. Creatinine and, to a lesser extent, BUN are correlated with GFR, but, as noted earlier, GFR must be reduced by 75% before azotemia is seen.
