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11 sty 2024 · 1. Arginine Vasopressin Deficiency (AVP-D, formerly known as Central Diabetes Insipidus or CDI) The preferred therapy is DDAVP. Typically, treatment is maintained for AVP-D, which varies depending on the cause. The minimum dose should be administered to control polyuria adequately.
Central diabetes insipidus (CDI) is a clinical syndrome which results from loss or impaired function of vasopressinergic neurons in the hypothalamus/posterior pituitary, resulting in impaired synthesis and/or secretion of arginine vasopressin (AVP).
Treatment of diabetes insipidus or primary polydipsia depends on the underlying aetiology and differs in central diabetes insipidus, nephrogenic diabetes insipidus and primary polydipsia. This review will discuss issues and newest developments in diagnosis, differential diagnosis and treatment, with a focus on central diabetes insipidus.
26 mar 2021 · The two main classifications of DI are central diabetes insipidus (CDI), characterized by a deficiency of the posterior pituitary gland to release ADH, and nephrogenic diabetes insipidus (NDI), characterized by the terminal distal convoluted tubule and collecting duct resistance to ADH.
We demonstrated the successful use of a novel AVP infusion protocol for the management of chronic DI in a. 27-hour facial transplantation surgery. This protocol may also be effective in managing other patients with chronic, unusual, and dificult-to-control DI during lengthy intraop-erative periods.
In this review, we will summarise the various diagnostic tests used to make the biochemical diagnosis of CDI, and the biochemical and radiological tests needed to identify the causation of AVP deficiency. We will also review the treatment strategies to manage polyuria, while avoiding hyponatraemia. 2 CAUSES OF CENTRAL DIABETES INSIPIDUS
This review will discuss issues and newest developments in diagnosis, differential diagnosis and treatment, with a focus on central diabetes insipidus. Keywords: copeptin; diabetes insipidus; diagnosis; primary polydipsia; water deprivation test.