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The well-recognized clinical association between HIV infection and iNTS disease, particularly among individuals with CD4 counts below 200 cells/µl, 42 also appears to provide clear support for the importance of cell mediated immunity in defense against Salmonella.
- Antimicrobial resistance and management of invasive Salmonella ... - PubMed
The main objective of this review is to describe existing...
- Salmonella Combination Vaccines: Moving Beyond Typhoid
While a trivalent typhoid/nontyphoidal Salmonella vaccine is...
- Advances in the development of Salmonella-based vaccine ... - PubMed
In this review we focus on (1) recent advances in live...
- Antimicrobial resistance and management of invasive Salmonella ... - PubMed
19 cze 2015 · The main objective of this review is to describe existing data on the prevalence and epidemiology of antimicrobial resistant invasive Salmonella infections and how this affects the management of these infections, especially in endemic developing countries.
2 cze 2023 · While a trivalent typhoid/nontyphoidal Salmonella vaccine is attractive for Africa, and a bivalent enteric fever vaccine for Asia, a quadrivalent vaccine covering the 4 main disease-causing serovars of Salmonella enterica would provide a single vaccine option for global Salmonella coverage.
There are currently three vaccines licensed for use in humans, all targeting typhoidal Salmonella: the live attenuated oral vaccine S. Typhi Ty21a, Vi capsule polysaccharide vaccine, and Vi polysaccharide conjugated with tetanus toxoid ( 11 – 14 ).
1 sty 2018 · Salmonella has been the most widely studied among bacterial genera for delivering recombinant protective Ags and DNA vaccine vectors because of its capacity to be delivered orally, thereby precluding the use of needles for immunization (16, 17, 21–37).
In this review we focus on (1) recent advances in live attenuated Salmonella vaccine development, (2) improvements in expression of foreign antigens in carrier vaccines and (3) adaptation of attenuated strains as sources of purified antigens and vesicles that can be used for subunit and conjugate vaccines or together with attenuated vaccine ...
Salmonella Vaccines. Though primarily enteric pathogens, Salmonellae are responsible for a considerable yet under-appreciated global burden of invasive disease. In South and South-East Asia, this manifests as enteric fever caused by serovars Typhi and Paratyphi A. In sub-Saharan Africa, a similar disease burden results …
